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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GIGYF2 All Species: 21.52
Human Site: S514 Identified Species: 47.33
UniProt: Q6Y7W6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6Y7W6 NP_001096616.1 1299 150070 S514 L D D E R L A S K L Q E H R A
Chimpanzee Pan troglodytes XP_001147956 1301 150322 S514 L D D E R L A S K L Q E H R A
Rhesus Macaque Macaca mulatta XP_001114387 1298 149954 S514 L D D E R L V S K L Q E H R A
Dog Lupus familis XP_861702 1296 149765 S514 L D D E R L A S K L Q E H R A
Cat Felis silvestris
Mouse Mus musculus Q6Y7W8 1291 149174 S515 L D D E R L T S K L Q E H R A
Rat Rattus norvegicus NP_001100603 1042 115996 T461 T Q G L R H S T A A T A L P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520911 674 76044 V188 F E E G G T T V T G R K H E F
Chicken Gallus gallus P53352 877 100922 R391 L R S Q T V N R N E Q Q Q E T
Frog Xenopus laevis Q5U236 1239 141618 T473 L D D D H L L T K V L D Q R V
Zebra Danio Brachydanio rerio Q4KME6 1335 153036 R537 D G G V D D E R L A S K I G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KQM6 1579 174343 I656 P L T A S L S I T P H K P S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99 97.4 N.A. 94.3 46.1 N.A. 46.9 20.5 60.9 61.2 N.A. 20.3 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 98.2 N.A. 95.6 58.7 N.A. 49.4 35.1 73.5 72.5 N.A. 38.3 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 6.6 N.A. 6.6 13.3 40 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 20 N.A. 33.3 33.3 66.6 6.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 28 0 10 19 0 10 0 0 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 55 55 10 10 10 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 10 10 46 0 0 10 0 0 10 0 46 0 19 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 19 10 10 0 0 0 0 10 0 0 0 10 0 % G
% His: 0 0 0 0 10 10 0 0 0 0 10 0 55 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 55 0 0 28 0 0 0 % K
% Leu: 64 10 0 10 0 64 10 0 10 46 10 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 10 0 0 10 10 19 % P
% Gln: 0 10 0 10 0 0 0 0 0 0 55 10 19 0 0 % Q
% Arg: 0 10 0 0 55 0 0 19 0 0 10 0 0 55 0 % R
% Ser: 0 0 10 0 10 0 19 46 0 0 10 0 0 10 0 % S
% Thr: 10 0 10 0 10 10 19 19 19 0 10 0 0 0 10 % T
% Val: 0 0 0 10 0 10 10 10 0 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _